Matthew E. Gegg: search on Z-Library

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1

Mitochondria: Key Organelle in Parkinson’s Disease

Gómez-Sánchez, Rubén, Bravo-San Pedro, José M., Gegg, Matthew E., González-Polo, Rosa A., Fuentes, José M.

Journal:

Parkinson's Disease

Year:

2016

Language:

english

File:

PDF, 1.15 MB

english, 2016

2

Glucocerebrosidase activity, cathepsin D and monomeric α-synuclein interactions in a stem cell derived neuronal model of a PD associated GBA1 mutation

Yang, Shi-yu, Gegg, Matthew, Chau, David, Schapira, Anthony

Journal:

Neurobiology of Disease

Year:

2020

Language:

english

File:

PDF, 4.24 MB

english, 2020

3

Determination of Glutamate-Cysteine Ligase (γ-Glutamylcysteine Synthetase) Activity by High-Performance Liquid Chromatography and Electrochemical Detection

Matthew E. Gegg, John B. Clark, Simon J.R. Heales

Journal:

Analytical Biochemistry

Year:

2002

Language:

english

File:

PDF, 91 KB

english, 2002

4

Preservation of extracellular glutathione by an astrocyte derived factor with properties comparable to extracellular superoxide dismutase

Victoria C. Stewart, Rebecca Stone, Matthew E. Gegg, Martyn A. Sharpe, Roger D. Hurst, John B. Clark, Simon J. R. Heales

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 216 KB

english, 2002

5

Probing minimal independent folding units in dihydrofolate reductase by molecular dissection

Colin V. Gegg, Katherine E. Bowers, C. Robert Matthews

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 2.64 MB

english, 1997

6

Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains

Matthew E. Gegg, Derek Burke, Simon J. R. Heales, J. Mark Cooper, John Hardy, Nicholas W. Wood, Anthony H. V. Schapira

Journal:

Annals of Neurology

Year:

2012

Language:

english

File:

PDF, 467 KB

english, 2012

7

Nerve Growth Factor, Central Nervous System Apoptosis, and Adrenocortical Activity in Aged Fischer-344/Brown Norway F1 Hybrid Rats

Giulio Taglialatela, Robert Robinson, Matthew Gegg, J.Regino Perez-Polo

Journal:

Brain Research Bulletin

Year:

1997

Language:

english

File:

PDF, 273 KB

english, 1997

8

PINK1-parkin-dependent mitophagy involves ubiquitination of mitofusins 1 and 2: Implications for Parkinson disease pathogenesis

Gegg, Matthew E., Schapira, Anthony H.V.

Journal:

Year:

2011

Language:

english

File:

PDF, 611 KB

english, 2011

9

Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease—Links to Parkinson’s Disease

Osellame, Laura D., Rahim, Ahad A., Hargreaves, Iain P., Gegg, Matthew E., Richard-Londt, Angela, Brandner, Sebastian, Waddington, Simon N., Schapira, Anthony H.V., Duchen, Michael R.

Journal:

Cell Metabolism

Year:

2013

Language:

english

File:

PDF, 3.28 MB

english, 2013

10

Accumulation of damaged mitochondria in neuropathic Gaucher disease, the most prevalent risk factor for Parkinson's disease, is due to defective cellular degradation machinery

Osellame, Laura D., Rahim, Ahad, Gegg, Matthew E., Waddington, Simon, Schapira, Anthony H.V., Duchen, Michael R.

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2012

Language:

english

File:

PDF, 83 KB

english, 2012

11

Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression

Gómez-Sánchez, Rubén, Gegg, Matthew E., Bravo-San Pedro, José M., Niso-Santano, Mireia, Alvarez-Erviti, Lydia, Pizarro-Estrella, Elisa, Gutiérrez-Martín, Yolanda, Alvarez-Barrientos, Alberto, Fuentes,

Journal:

Neurobiology of Disease

Year:

2014

Language:

english

File:

PDF, 2.23 MB

english, 2014

12

Glucocerebrosidase in the pathogenesis and treatment of Parkinson disease: Fig. 1.

Schapira, Anthony H. V., Gegg, Matthew E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 569 KB

english, 2013

13

Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death

Keatinge, Marcus, Bui, Hai, Menke, Aswin, Chen, Yu-Chia, Sokol, Anna M., Bai, Qing, Ellett, Felix, Da Costa, Marc, Burke, Derek, Gegg, Matthew, Trollope, Lisa, Payne, Thomas, McTighe, Aimee, Mortiboys

Journal:

Human Molecular Genetics

Year:

2015

Language:

english

File:

PDF, 1.15 MB

english, 2015

14

Endoplasmic reticulum and lysosomal Ca2+ stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts

Kilpatrick, Bethan S., Magalhaes, Joana, Beavan, Michelle S., McNeill, Alisdair, Gegg, Matthew E., Cleeter, Michael W.J., Bloor-Young, Duncan, Churchill, Grant C., Duchen, Michael R., Schapira, Anthon

Journal:

Year:

2016

Language:

english

File:

PDF, 2.66 MB

english, 2016

15

Semiconductor Quantum Dot Lifetime Near an Atomically Smooth Ag Film Exhibits a Narrow Distribution

Hartsfield, Thomas, Gegg, Michael, Su, Ping-Hsiang, Buck, Matthew, Hollingsworth, Jennifer A., Shih, Chih-Kang, Richter, Marten, Htoon, Han, Li, Xiaoqin

Journal:

Year:

2016

Language:

english

File:

PDF, 1.01 MB

english, 2016

16

Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy

Ivankovic, Davor, Chau, Kai-Yin, Schapira, Anthony H. V., Gegg, Matthew E.

Journal:

Journal of Neurochemistry

Year:

2016

Language:

english

File:

PDF, 2.26 MB

english, 2016

17

Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson Disease

Magalhaes, Joana, Gegg, Matthew E., Migdalska-Richards, Anna, Doherty, Mary K., Whitfield, Phillip D., Schapira, Anthony H.V.

Journal:

Human Molecular Genetics

Year:

2016

Language:

english

File:

PDF, 1.85 MB

english, 2016

18

Evidence for DNA fragmentation in the CNS of aged Fischer-344 rats

Taglialatela, Giulio, Gegg, Matthew, Perez-Polo, J. Regiono, Williams, Lawrence R., Rose, Gregory M.

Journal:

Year:

1996

File:

PDF, 315 KB

1996

19

No evidence for substrate accumulation in Parkinson brains with GBA mutations

Gegg, Matthew E., Sweet, Lindsay, Wang, Bing H., Shihabuddin, Lamya S., Sardi, Sergio Pablo, Schapira, Anthony H.V.

Journal:

Movement Disorders

Year:

2015

Language:

english

File:

PDF, 255 KB

english, 2015

20

Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models

Sanchez-Martinez, Alvaro, Beavan, Michelle, Gegg, Matthew E., Chau, Kai-Yin, Whitworth, Alexander J., Schapira, Anthony H. V.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.65 MB

english, 2016

21

The role of glucocerebrosidase in Parkinson disease pathogenesis

Gegg, Matthew E., Schapira, Anthony H.V.

Journal:

Year:

2018

Language:

english

File:

PDF, 302 KB

english, 2018

22

Bioenergetic Consequences of PINK1 Mutations in Parkinson Disease

Abramov, Andrey Yurevich, Gegg, Matthew, Grunewald, Anne, Wood, Nicholas William, Klein, Christine, Schapira, Anthony Henry Vernon, Mattson, Mark P.

Journal:

Year:

2011

Language:

english

File:

PDF, 624 KB

english, 2011

23

Mitochondrial Contribution to Parkinson's Disease Pathogenesis

Schapira, Anthony H. V., Gegg, Matthew

Journal:

Parkinson's Disease

Year:

2011

Language:

english

File:

PDF, 1.19 MB

english, 2011

24

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging || Ubiquitination of Mitofusins in PINK1/Parkin-Mediated Mitophagy

Gegg, Matthew E.

Year:

2014

Language:

english

File:

PDF, 471 KB

english, 2014

25

Glucocerebrosidase deficiency promotes release of Î±-synuclein fibrils from cultured neurons

Gegg, Matthew E, Verona, Guglielmo, Schapira, Anthony H V

Journal:

Human Molecular Genetics

Year:

2020

File:

PDF, 1.00 MB

2020